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Nanjing Zelang Medical Technology Co., Ltd.

Mucuna Pruriens Extract, Natural Mucuna Pruriens Extract, L-Dopa manufacturer / supplier in China, offering Mucuna Pruriens Extract Levodopa 98%, Sweeteners Xylitol (CAS No.: 87-99-0), Nutritional Supplement Chondroitin Sulfate (USP32) and so on.

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Mucuna Pruriens Extract Levodopa 98%

Purchase Qty.:
(KG)
1-99 100+
FOB Unit Price: US $1 US $100
Purchase Qty. (KG) FOB Unit Price
1-99 US $1
100+ US $100
Get Latest Price
Production Capacity: 100kg/Month
Transport Package: Aluminum Foil Vacuum Bag/ Drum
Payment Terms: L/C, T/T, Paypal, Western Union, STS/ESCROW

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Basic Info
  • Model NO.: 59-92-7
  • Name: Levodopa
  • Purity: 98%
  • Trademark: CPE
  • Origin: Nanjing, China
  • Raw Material: Plants
  • Appearance: White Powder
  • Test Method: HPLC
  • Specification: ISO. SGS. BV
  • HS Code: 2932999099
Product Description

Description:
 
 

Name:

levodopa

CAS No:

59-92-7

Appearance:

Gray white powder

Molecular Formula:

C9H11NO4

Molecular Weight:

197.19

Herb Sourse:

Seed of Mucuna macrocarpa Wall

Content:

99%

Active ingredient:

Levodopa

Shelf Life:

2 years when properly stored.

Storage:

Cool and dry place,keep away from strong light & high temp

Melting Point:

285~288°C

Package:

25kg or 30kg/drum,or as per your requests.

Solubility:

Insoluble in water,soluble in ethanol, no extraneous substance after being dissolved.

 
Application:
Levodopa is used to increase dopamine levels for the treatment of Parkinson's disease and dopamine-responsive dystonia, since it is able to cross the blood-brain barrier, whereas dopamine itself cannot. Once levodopa has entered the central nervous system (CNS), it is metabolized to dopamine by aromatic L-amino acid decarboxylase. Pyridoxal phosphate (vitamin B6) is a required cofactor for this decarboxylation, and may be administered along with levodopa, usually as pyridoxine. 

Conversion to dopamine also occurs in the peripheral tissues, i.e., outside the brain. This may be the mechanism of the adverse effects of levodopa, listed below. It is standard clinical practice to co-administer a peripheral DOPA decarboxylase inhibitor,carbidopa or benserazide,and often a catechol-O-methyl transferase (COMT) inhibitor, like entacapone, to prevent synthesis of dopamine in peripheral tissue. Co-administration of pyridoxine without a decarboxylase inhibitor accelerates the extracerebral decarboxylation to such an extent that it cancels out the effects of levodopa administration, a circumstance that historically caused great confusion.
 
L-DOPA (3,4-dihydroxy-L-phenylalanine) is a naturally occurring amino acid found in food and made from L-Tyrosine in the human body. L-DOPA is converted into dopamine in the brain and body. It is sold as a dietary supplement and as a prescription drug in the US. In clinical use, Levodopa (INN) is administered in the management of Parkinson's disease and dopa-responsive dystonia. It is also used as a component in marine adhesives used by pelagic life.
 
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